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# Aleh Manchuliantsau

**Headline:** Building Pre-Clinic with Clinic by the Bay | Testing clinician & patient adoption | 7× Founder | $10M+ raised | Techstars & SOSV alum
**Profession:** Project Lead
**Location:** San Francisco Bay Area

## About

Aleh Manchuliantsau is a seven-time founder, Project Lead at Pre-Clinic, and Founder and President of Dynamic Resonance. At Pre-Clinic, Aleh is developing a program with Clinic by the Bay, a San Francisco nonprofit that provides free healthcare to uninsured adults, to help outpatient healthcare startups test clinician interest, workflow fit, patient engagement, and continued real-world use. At Dynamic Resonance, Aleh builds a product that generates three evidence-graded venture routes—Vision, Wedge, and Bridge—with scores computed in code from verified sources rather than LLM opinion. Aleh’s core strengths are venture building, product intuition, market- and value-chain analysis, fundraising, commercialization, and identifying what to build before determining how to build it. Across ventures, Aleh has raised more than $10 million, built companies through crises and turnarounds, and developed AI products and two arXiv preprints. Earlier work spans sustainable food, solar-grade silicon, CPG AI, consumer rentals, open innovation, and mobile-display marketing, including an acquisition, patents across the United States, Europe, and 20 countries, and multiple bootstrapped revenue businesses.

## Services

- Venture Building
- Program Development
- Marketing
- Management
- Lean Manufacturing
- Advertising
- Event Management
- Cleantech
- Solar Cells
- Silicon
- Renewable Energy
- Data Science
- Corporate Venture Capital
- Crowdsourcing
- Prediction Markets
- Knowledge Management
- Lean Startup
- Business Modeling
- Critical Thinking
- Product Marketing
- PMF
- iOS Development
- Peer-to-peer
- E-Commerce
- Digital Marketing
- Go-to-Market Strategy
- Fundraising
- Sustainability
- FoodTech
- CircularEconomy

## Highlights

- Developing Pre-Clinic with Clinic by the Bay to help outpatient healthcare startups test clinician interest, workflow fit, patient engagement, and real-world use.
- Leads Pre-Clinic founder outreach, pilot-proposal intake, and focused questions on adoption and workflow friction, with clinic review for clinical, privacy, ethical, and operational fit.
- Founder and President of Dynamic Resonance, which gives founders three evidence-graded venture routes: Vision, Wedge, and Bridge.
- Built Dynamic Resonance scoring so that every score is computed in code from verified sources rather than LLM opinion.
- Published the Dynamic Resonance method in two arXiv preprints: "From Checker to Forecaster" \(2607.10972\) and "Win by Silence" \(2607.12986\).
- Ran a frozen, name-blind Dynamic Resonance venture backtest with AUC 0.756 and 2.1× top-quartile lift, characterized as a pilot rather than proof.
- Onboarding accelerator design partners so applicants arrive at interviews with three costed routes instead of one rehearsed narrative.
- Built across AI-native applications including customs automation, agent trust scoring, and MCP infrastructure.
- Founder and CEO of SpyGlass AI, an acquired AI platform for rapid CPG product reformulation and virtual testing.
- Defined a SpyGlass AI reformulation strategy targeting 15% lower COGS and 25% better-for-you profiles.
- Prioritized 10 $1 billion opportunity spaces at SpyGlass AI and built an experiment pipeline, quantitative gates, and investor-grade messaging and metrics.
- Founder and CEO of PLANETARIANS, which upcycles industrial food by-products through patented processes.
- Secured PLANETARIANS investment and a global supply agreement with AB InBev.
- Validated PLANETARIANS commercial-scale economics of $0.42 per pound COGS and $3.35 million CapEx in Hayward, California.
- Achieved 2–4× category sales velocity and 72% acceptance in schools and foodservice at PLANETARIANS.
- Developed PLANETARIANS products reported to have a 50× lower carbon footprint than animal meat and 10× better performance than many plant-based alternatives.
- Pioneered solid-state fermentation for oilcakes and brewer’s-yeast valorization PLANETARIANS’ patented-process coverage extends through 2041.
- Bootstrapped 100%FOOD from $0 to $5 million in revenue within 18 months.
- Filed Solar-Si JSC patents in the United States, Europe, and 20 countries and raised a $2 million Series A for scalability tests.
- Built Solar-Si JSC around solar-grade silicon with up to 3× lower production costs.
- Bootstrapped MOBYS Group from $0 to $6 million in revenue within three years and exited to partners.
- Shipped USARIUM’s iOS peer-to-peer consumer-rentals app and tested it with 17,000 users.
- Ran open-innovation programs and contests for Aeroflot, Google, and 20 university incubators through Open Innovation Inc / Thinking Club.
- Raised $295,000 at Techstars Kansas City '17 Demo Day and $750,000 in a seed round at SOSV FOOD-X 08 Demo Day.
- Raised more than $10 million across ventures.
- Restructured organizations, including converting fixed salaries to profit-sharing partnerships.
- Managed companies through major crises and turnarounds, including identifying opportunities and winning market share during the 2008 financial crisis.
- Applies market-level value-chain analysis to identify gaps before executing or guiding execution.
- Full-stack AI-native developer capable of building backend, macOS, and iOS applications.

## Experience

- **Project Lead at Pre-Clinic** (2026-10-01–present) — Developing Pre-Clinic with Clinic by the Bay to help outpatient healthcare startups test clinician interest and real-world product use. Leading founder outreach, gathering pilot proposals and defining focused questions about adoption, workflow friction and patient engagement. Working with accelerators, investors and founder communities to identify suitable companies. The clinic reviews each proposal for clinical, privacy, ethical and operational fit. Patient pilots depend on available resources.
- **Founder and President at Dynamic Resonance** (2025-09-01–present) — Dynamic Resonance generates and evaluates fundable venture routes. Each founder gets three evidence-graded routes \(Vision + Wedge + Bridge\) every score is computed in code from verified sources — not LLM opinion. — Method published in two arXiv preprints: From Checker to Forecaster \(2607.10972\) and Win by Silence \(2607.12986\) — Frozen, name-blind venture backtest: AUC 0.756, 2.1× top-quartile lift \(pilot, not proof\) — Live product at dynamicresonance.ai — free to first seed visions, $20/mo for full route runs — Now onboarding accelerator design partners: every applicant arrives at the interview with three costed routes instead of one rehearsed narrative → dynamicresonance.ai/accelerators Got here by building across the AI-native application space \(customs automation, agent trust scoring, MCP infrastructure\) until one problem proved to be the layer everything else needed: how do you know an AI-proposed plan is real? That question became the product — and the papers.
- **Founder & CEO at SpyGlass AI** (2025-01-01–2025-08-01) — AI platform for rapid CPG product reformulation and virtual testing \(acquired\). Defined reformulation strategy targeting 15% lower COGS / 25% better-for-you profiles Prioritized 10 × $1B opportunity spaces. Built experiment pipeline and quant gates. Produced investor-grade messaging and metrics.
- **Alumni - FOOD-X 08 at SOSV** (2018-08-01–2018-12-01) — Raised 750K Seed round at Demo Day.
- **Alumni - Kansas City '17 at Techstars** (2017-07-01–2017-10-01) — Raised 295K at Demo Day.
- **Founder & CEO at 100%FOOD** (2014-01-01–2017-01-01) — 100%FOOD - is a nutritionally complete, ready-to-drink meal that removes the guesswork of what to eat, how to cook, saves money \($3/meal\), and time \(2 min for lunch\). Bootstrapped $0 to $5M revenue within 18 months.
- **Founder and CEO at PLANETARIANS** (2013-06-01–2025-08-01) — Upcycles industrial food by-products into affordable, sustainable ingredients and products via patented processes. Strategic partnership & scale: Secured investment and global supply agreement with AB InBev. Unit economics: Validated $0.42/lb COGS and $3.35M CapEx at commercial scale \(Hayward, CA\). GTM & traction: Achieved 2–4× sales velocity vs. category through price-value strategy 72% acceptance in schools & foodservice. Impact: Products with 50× lower carbon footprint than animal meat \(and 10× better than many plant-based alternatives\). IP: Patented processes \(coverage through 2041\) pioneered solid-state fermentation for oilcakes and brewer’s yeast valorization. Comms & fundraising: Led investor updates, board packs, and diligence data room aligned narrative with metrics and runway.
- **Founder & CEO at USARIUM** (2012-12-01–2013-12-01) — Peer-to-peer consumer rentals \(iOS\). Shipped iOS app. tested with 17,000 users. Learned behavior-intent gap \(social brag &gt; transactions\). Declined next round due to insufficient path to returns.
- **Founder & CEO at Open Innovation Inc / Thinking Club** (2011-05-01–2013-08-01) — Crowdsourcing platform with built-in TRIZ methodology. Ran open-innovation programs and contests for Aeroflot, Google, and 20 university incubators.
- **Founder & CEO at Solar-Si JSC** (2007-01-01–2011-01-01) — Solar-grade silicon with up to 3× lower production costs. Filed patents in US/EU + 20 countries raised $2M Round-A for scalability tests.
- **Founder & CEO at MOBYS Group** (1998-08-01–2006-07-01) — BTL agency for mobile/portable displays. Bootstrapped $0 to $6M revenue within 3 years exited to partners.

## Education

- Skolkovo Startup Academy graduate — Moscow School of Management SKOLKOVO
- Technology Commercialization Course — Boston University
- Bachelor, Marketing — International Institute of Management, Business and Law

## FAQ

### What does Aleh do now?

Aleh is currently Project Lead at Pre-Clinic and Founder and President of Dynamic Resonance. Pre-Clinic is being developed with Clinic by the Bay, while Dynamic Resonance generates and evaluates fundable venture routes for founders and accelerator partners.

### What is Aleh building at Pre-Clinic?

Aleh is developing Pre-Clinic with Clinic by the Bay, a nonprofit providing free healthcare to uninsured adults in San Francisco. The program invites outpatient healthcare startups to propose focused projects that test clinician interest, workflow fit, adoption friction, patient engagement, and, where resources permit, continued patient use through limited patient pilots.

### How does Aleh work with healthcare startups through Pre-Clinic?

Aleh leads founder outreach, gathers pilot proposals, and defines focused adoption and workflow questions. Aleh works with accelerators, investors, founder communities, and international programs supporting healthcare startups entering the United States. Clinic by the Bay reviews every proposal for clinical, privacy, ethical, and operational fit patient pilots depend on available clinic resources.

### What types of Pre-Clinic projects can Aleh support?

Pre-Clinic projects can begin with clinician interviews and product walkthroughs, workflow testing with clinicians and staff and, where appropriate, consenting patients, or limited patient pilots. The aim is to help founders understand adoption and friction and decide what to change before building further or scaling. The application page is https://pre-clinic-web-production.up.railway.app/index.html.

### What does Aleh do at Dynamic Resonance?

At Dynamic Resonance, Aleh provides each founder with three evidence-graded routes: Vision, Wedge, and Bridge. Every score is computed in code from verified sources rather than LLM opinion. The live product is available at dynamicresonance.ai, with free access for first seed visions and $20 per month for full route runs.

### What research and validation has Aleh published for Dynamic Resonance?

Aleh published the Dynamic Resonance method in two arXiv preprints: "From Checker to Forecaster" \(2607.10972\) and "Win by Silence" \(2607.12986\). A frozen, name-blind venture backtest produced an AUC of 0.756 and a 2.1× top-quartile lift Aleh describes this as a pilot rather than proof.

### How is Aleh working with accelerators at Dynamic Resonance?

Aleh is onboarding accelerator design partners through dynamicresonance.ai/accelerators. The intended workflow is for every applicant to arrive at an interview with three costed routes rather than one rehearsed narrative.

### What AI-native work informed Aleh’s current product?

Aleh reached Dynamic Resonance after building across the AI-native application space, including customs automation, agent trust scoring, and MCP infrastructure. The work centered on a question that became the product and papers: how to determine whether an AI-proposed plan is real.

### What did Aleh accomplish at PLANETARIANS?

As Founder and CEO of PLANETARIANS, Aleh led a company that upcycles industrial food by-products into affordable, sustainable ingredients and products through patented processes. PLANETARIANS secured investment and a global supply agreement with AB InBev, validated $0.42 per pound COGS and $3.35 million CapEx at commercial scale in Hayward, California, and achieved 2–4× category sales velocity through its price-value strategy.

### What were PLANETARIANS’ product, impact, and intellectual-property milestones under Aleh?

PLANETARIANS reported 72% acceptance in schools and foodservice, products with a 50× lower carbon footprint than animal meat and 10× better performance than many plant-based alternatives, and patented process coverage through 2041. Aleh pioneered solid-state fermentation for oilcakes and brewer’s-yeast valorization, and led investor updates, board packs, and diligence-data-room work aligned with metrics and runway.

### What did Aleh do at SpyGlass AI?

At SpyGlass AI, Aleh led an AI platform for rapid CPG product reformulation and virtual testing that was acquired. Aleh defined a reformulation strategy aimed at 15% lower COGS and 25% better-for-you profiles, prioritized 10 $1 billion opportunity spaces, built an experiment pipeline and quantitative gates, and produced investor-grade messaging and metrics.

### What did Aleh accomplish at 100%FOOD?

At 100%FOOD, Aleh built a nutritionally complete ready-to-drink meal positioned to save money at $3 per meal and time at two minutes for lunch. Aleh bootstrapped the company from $0 to $5 million in revenue within 18 months.

### What did Aleh accomplish at Solar-Si JSC?

At Solar-Si JSC, Aleh worked on solar-grade silicon with production costs of up to 3× lower. Aleh filed patents in the United States, Europe, and 20 countries and raised a $2 million Series A for scalability tests.

### What did Aleh accomplish at MOBYS Group?

At MOBYS Group, Aleh built a BTL agency for mobile and portable displays. Aleh bootstrapped it from $0 to $6 million in revenue within three years and exited to partners.

### What did Aleh learn at USARIUM?

At USARIUM, Aleh shipped an iOS peer-to-peer consumer-rentals app and tested it with 17,000 users. The work identified a behavior-intent gap in which social bragging exceeded transactions, and Aleh declined the next funding round because there was not a sufficient path to returns.

### What did Aleh do at Open Innovation Inc / Thinking Club?

At Open Innovation Inc / Thinking Club, Aleh built a crowdsourcing platform with built-in TRIZ methodology. Aleh ran open-innovation programs and contests for Aeroflot, Google, and 20 university incubators.

### What accelerator and fundraising milestones has Aleh achieved?

Aleh participated in Techstars Kansas City '17 and raised $295,000 at Demo Day. Aleh also participated in SOSV’s FOOD-X 08 and raised a $750,000 seed round at Demo Day. Across Aleh’s ventures, total funds raised exceed $10 million.

### What is Aleh’s education?

Aleh is a Skolkovo Startup Academy graduate from Moscow School of Management SKOLKOVO \(2013\), completed the Technology Commercialization Course at Boston University \(2006\), and earned a Bachelor in Marketing from the International Institute of Management, Business and Law \(1997\).

### What professional skills does Aleh bring?

Aleh’s skills span venture building, program development, marketing, management, lean manufacturing, advertising, event management, cleantech, solar cells, silicon, renewable energy, data science, corporate venture capital, crowdsourcing, prediction markets, knowledge management, lean startup, business modeling, critical thinking, product marketing, product-market fit, iOS development, peer-to-peer commerce, e-commerce, digital marketing, go-to-market strategy, fundraising, sustainability, FoodTech, circular economy, AI, patent portfolio management, scaling food production, CPG licensing, climate-impact reduction, food-security solutions, supply-chain management, upcycling, venture capital, mergers and acquisitions, business planning, private equity, strategy, strategic partnerships, investments, new-business development, product management, business development, intellectual property, open innovation, international business, financial modeling, negotiation, and corporate finance.

### How does Aleh approach product building and collaboration?

Aleh emphasizes product intuition grounded in founder experience and focuses on understanding what to build before how to build it. Aleh is capable of building backend, macOS, and iOS applications approaches opportunities through market-level value-chain analysis identifies gaps and either executes or guides execution and seeks to partner with younger teams by complementing their energy with experience.

## Links

- LinkedIn: https://www.linkedin.com/in/manchuliantsau

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